In this issue of BioTechniques, we explore various topics related to advanced biotechnology research. One of the main focuses is on quality control mechanisms in mitochondrial transplantation, which is a cutting-edge technique used in personalized medicine. Additionally, we discuss a protocol for extracting RNA from formaldehyde-fixed neuromusculoskeletal tissue and how a HeLa cell extract-derived cell-free protein synthesis system can be utilized to study protein complexes and RNA viruses.
The Technology News section covers the latest advancements in recording the brain in vivo, with a specific focus on emerging technologies for exploring mental health conditions. The Editorial section provides insights and considerations for developing mitochondrial transplantation techniques for individualized medicine.
Reports in this issue include an industry perspective on the implementation of ready-to-use cells in bioassays, as well as a multiparameter screen that optimizes immunoprecipitation. Another report details a protocol for extracting high-quality RNA from formaldehyde-fixed naturally aged neuromusculoskeletal tissues. Additionally, a high-throughput screening method for a SARS-CoV-2 frameshifting inhibitor using a cell-free protein synthesis system is discussed.
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