- Evaxion created a genetic adjuvant technologies that boosts the immune responses of viral, bacterial and cancer vaccines
- Preclinically validated for each DNA and mRNA vaccines, and prepared for clinical testing
- Anticipated substantial marketplace possible for DNA and mRNA vaccines against cancer, viral and bacterial ailments
COPENHAGEN, Denmark, Might 25, 2023 (GLOBE NEWSWIRE) — Evaxion Biotech A/S (NASDAQ: EVAX) (“Evaxion” or the “Company”), a clinical-stage biotechnology organization specializing in the discovery and improvement of AI-powered immunotherapies, right now unveils the technologies behind its novel, proprietary genetic adjuvant created to improve the effectiveness of DNA and mRNA vaccines for infectious ailments and cancer.
Most recent information from the adjuvant plan had been presented at Evaxion’s reside stream R&D Day, Might 25, 2023.
“We are excited to present this novel genetic adjuvant technologies to the international scientific neighborhood. It boosts Evaxion´s personal DNA technologies and has the possible to increase the impact of practically any vaccine. We foresee a fantastic marketplace possible in that this technologies seems to be very helpful in each DNA and mRNA primarily based vaccines against cancer as properly as infectious ailments,” mentioned Per Norlén, CEO at Evaxion.
Evaxion´s novel genetic adjuvant carries the code for CCL19, a molecule recognized to attract immune cells, notably antigen presenting cells, and can be encoded into either DNA or mRNA vaccines with the aim of boosting the immune response.
Most recent information show that the genetic adjuvant technologies boosts the antitumor impact in preclinical tumor models, and induces neutralizing antibodies and T-cell responses against each viral and bacterial antigens:
Per Norlén continues, “By encoding the immune-stimulating molecule CCL19 into either DNA or mRNA vaccines, we have demonstrated substantial enhancement of the vaccines effectiveness. We think that this advancement holds immense possible for vaccine improvement, as it boosts each B cell and T cell immune responses, creating it applicable to a wide variety of vaccines. Creating on the encouraging preclinical benefits, the subsequent step is to validate the technologies in sufferers.”
Evaxion aims to bring the genetic adjuvant technologies into clinical trials later this year as portion of the customized cancer immunotherapy plan EVX-03.
Please check out the Investors section of Evaxion’s internet site to access a replay of the R&D Day presentations.
Evaxion Biotech A/S is a pioneering organization creating AI-powered immunotherapies. Evaxion’s proprietary and scalable AI technologies decode the human immune method to uncover and create novel immunotherapies for cancer, bacterial ailments, and viral infections. Evaxion has a broad pipeline of candidates, which includes 3 customized cancer immunotherapies. It is situated in Hørsholm, Denmark, with 50 workers listed on the Nasdaq New York stock exchange. For far more information and facts, please check out www.evaxion-biotech.com.
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