According to The Wall Street Journal, researchers in Italy have found a prospective hyperlink in between Neanderthal genes and extreme situations of COVID-19. Their study examined the DNA of almost 1,200 volunteers in a heavily impacted province throughout the early stages of the pandemic. The outcomes indicated that folks with genetic variants related with Neanderthal ancestry had been far more most likely to encounter extreme symptoms that necessary hospitalization. In truth, the researchers discovered that the Neanderthal haplotype, a set of genetic variants, was a big genetic threat element for extreme COVID-19. Folks with this haplotype had been twice as most likely to create extreme pneumonia and 3 instances as most likely to call for ventilator assistance in an intensive care unit.
The connection in between Neanderthal DNA and overall health has been recommended in other research as effectively. A study published in Molecular Biology and Evolution discovered a hyperlink in between Neanderthal DNA and a genetic disorder known as Dupuytren’s illness, even though a study published in Nature found a connection in between Neanderthal ancestry and an improved threat of an intense immune response, recognized as a cytokine storm, in people today who contract COVID-19.
These findings shed light on the effect of Neanderthal genes on human overall health, specifically in the context of COVID-19. It highlights the value of understanding genetic variations as prospective threat variables for extreme situations of the virus. Additional investigation in this location may well present insights into prospective therapies or preventive measures for folks at larger threat due to their genetic makeup.